
7 Supplements Proven to Increase Testosterone
Evidence-based natural compounds that boost testosterone through specific biological mechanisms, backed by clinical research and real-world results.
The Modern Testosterone Crisis
Modern men's testosterone levels have dropped by 20-30% over the past three decades. Environmental toxins, chronic stress, poor sleep, and sedentary lifestyles all contribute to this hormonal decline that affects energy, muscle mass, mood, and overall vitality.
While synthetic hormone replacement therapy exists, natural supplementation offers a safer, more sustainable approach to optimizing testosterone production. The key is targeting different biological pathways that support your body's natural hormone manufacturing process.
The following seven supplements have robust clinical research demonstrating their ability to increase testosterone levels through specific, measurable mechanisms. Each targets a different pathway, making them highly effective when used individually or in combination.

Ashwagandha KSM-66: The Stress-Fighting Testosterone Booster
Ashwagandha works by reducing cortisol, your primary stress hormone that directly suppresses testosterone production. When cortisol levels drop, your body can produce testosterone more efficiently.
The Science: Clinical studies show KSM-66 ashwagandha can increase testosterone levels by 14-40% in just 8 weeks. Participants also experienced improved muscle mass, strength, and reduced stress markers.
- Dosage: 600mg daily of KSM-66 extract specifically
- Timing: Morning or evening with food
- Benefits: Stress reduction + testosterone boost
- Results: Noticeable within 2-4 weeks
KSM-66 is the most researched form of ashwagandha with the highest concentration of active compounds. Unlike generic ashwagandha, KSM-66 is specifically standardized for bioactive withanolides that deliver consistent results.

Tongkat Ali: The Free Testosterone Liberator
Tongkat Ali works through two pathways: it reduces SHBG (sex hormone binding globulin) that binds testosterone, making it unavailable, and stimulates LH (luteinizing hormone) production, which signals your body to produce more testosterone.
The Science: Andrew Huberman recommends Tongkat Ali based on studies showing significant increases in free testosterone, the bioactive form your body can actually use. Research shows 200-400mg daily can improve testosterone status in men with low levels.
- Dosage: 200-400mg daily of standardized extract
- Timing: Empty stomach for better absorption
- Cycling: 4 weeks on, 1 week off recommended
- Benefits: Free testosterone increase + libido boost
"Tongkat Ali has good evidence for increasing free testosterone, which is really what you care about."
Traditional Southeast Asian medicine has used Tongkat Ali for centuries to enhance male vitality. Modern research validates this traditional use, showing it's particularly effective for men over 30 when natural testosterone production begins declining.

Fadogia Agrestis: The LH Stimulator
Fadogia Agrestis works by directly stimulating luteinizing hormone (LH) production in the pituitary gland. LH is the signal that tells your testes to produce testosterone, making this a powerful upstream approach to hormone optimization.
The Science: Research shows Fadogia Agrestis can significantly increase testosterone levels and improve sexual performance. Studies indicate 600mg daily provides optimal results for enhancing natural hormone production without side effects.
- Dosage: 600mg daily of stem extract
- Timing: Empty stomach for better absorption
- Cycling: 4 weeks on, 1 week off recommended
- Benefits: LH stimulation + testosterone boost + libido enhancement
Fadogia Agrestis is particularly effective when combined with Tongkat Ali, as they work through complementary pathways. While Tongkat Ali reduces SHBG to free up bound testosterone, Fadogia Agrestis stimulates the production of new testosterone at the source.
Traditional Nigerian medicine has used Fadogia Agrestis for male fertility and vitality. The stem extract contains bioactive compounds that specifically target the hypothalamic-pituitary-gonadal axis, making it one of the most direct natural approaches to testosterone optimization.

Mucuna Pruriens: The Prolactin Suppressor
Mucuna Pruriens contains natural L-DOPA, which reduces prolactin levels. High prolactin acts like a "brake" on testosterone production, so lowering it allows your natural hormone production to increase.
The Science: Studies show that men with elevated prolactin have significantly lower testosterone. Mucuna Pruriens' L-DOPA content naturally reduces prolactin while simultaneously boosting dopamine, improving both hormones and mood.
- Dosage: 300-500mg daily (15% L-DOPA standardized extract)
- Timing: Morning on empty stomach for dopamine boost
- Benefits: Testosterone optimization + motivation increase
- Bonus: Enhanced mood and drive from dopamine support
This supplement offers a unique dual benefit. Not only does it support testosterone production by removing prolactin inhibition, but the dopamine boost improves motivation, focus, and overall drive. It's particularly valuable for men dealing with stress-related hormonal imbalances.
Look for extracts standardized to 15% L-DOPA content for therapeutic effectiveness. Lower concentrations may not provide sufficient prolactin-lowering effects.

Boron: The Estrogen Blocker
Boron works through two critical pathways: it reduces SHBG (freeing up bound testosterone) and inhibits aromatase enzyme activity, which prevents testosterone from being converted into estrogen.
The Science: Research shows 10mg of boron daily can increase free testosterone by 28% within just one week. It also reduces estradiol (estrogen) levels by 39%, creating an optimal hormonal environment for male performance.
- Dosage: 10mg daily (not the 3mg found in most multivitamins)
- Timing: With meals to enhance absorption
- Speed: Effects noticeable within days, not weeks
- Benefit: Immediate free testosterone optimization
Boron is incredibly cost-effective and one of the cheapest testosterone-optimizing supplements with some of the fastest results. The key is getting the therapeutic 10mg dose, not the inadequate amounts found in typical multivitamins.
This mineral is particularly valuable for men over 35 when aromatase enzyme activity increases, leading to more testosterone being converted to estrogen. Boron helps maintain the optimal testosterone-to-estrogen ratio.

Astaxanthin: The Leydig Cell Protector
Astaxanthin is a unique antioxidant that specifically protects Leydig cells in the testes, which are the cells that actually produce testosterone. It also supports healthy DHT conversion while protecting against oxidative damage.
The Science: Studies show astaxanthin protects testosterone-producing cells from oxidative stress and inflammation, which can severely damage hormone production. It's 6,000 times more powerful than vitamin C as an antioxidant.
- Dosage: 8-12mg daily of high-potency extract
- Timing: With fats/oils for better absorption
- Benefits: Cellular protection + hormone optimization
- Bonus: Skin protection and anti-aging effects
What makes astaxanthin unique is its specific affinity for protecting the cellular machinery that produces hormones. While other antioxidants offer general protection, astaxanthin concentrates in tissues that matter most for testosterone production.
This supplement offers benefits beyond testosterone as one of the most powerful anti-aging compounds available, protecting skin from UV damage and supporting overall cellular health. It's particularly valuable for active men who generate more oxidative stress.
Why NUTREX HAWAII BioAstin: This Hawaiian-grown astaxanthin is farm-direct from clean Pacific waters, ensuring maximum potency and purity. At 12mg per capsule, it delivers therapeutic doses without synthetic additives. The controlled cultivation process produces higher concentrations of bioactive compounds compared to cheaper alternatives sourced from polluted waters.

Zinc: The Foundation Mineral
Zinc is an essential cofactor in testosterone synthesis. Without adequate zinc, your body simply cannot produce testosterone efficiently. It's required for over 300 enzymatic processes involved in hormone production.
The Science: Zinc deficiency directly correlates with low testosterone levels. Studies show that men with adequate zinc status have significantly higher testosterone than those who are deficient. Supplementation can restore levels in deficient men.
- Dosage: 15-30mg daily (balance with 2mg copper)
- Timing: Away from calcium and iron for better absorption
- Form: Zinc picolinate or bisglycinate for superior bioavailability
- Warning: Don't exceed 40mg daily without copper balance
Zinc is the foundation that all other testosterone optimization efforts build upon. You cannot optimize hormone production if you're deficient in this essential mineral. It's particularly important for men who sweat regularly through exercise, as zinc is lost through perspiration.
Always pair zinc with copper in a 10:1 or 15:1 ratio to prevent copper deficiency, which can occur with high-dose zinc supplementation. Look for chelated forms like picolinate or bisglycinate for maximum absorption and minimal digestive upset.
Optimal Stacking and Timing Protocol
For maximum effectiveness, these supplements can be combined since they target different biological pathways. However, start with 2-3 supplements initially to assess tolerance and individual response before adding others.
Beginner Stack: Start with Ashwagandha KSM-66 + Zinc + Boron. This combination addresses the most common issues (stress, deficiency, estrogen conversion) with minimal interaction risk.
- Morning (empty stomach): Tongkat Ali, Fadogia Agrestis, Mucuna Pruriens
- Morning (with food): Ashwagandha, Boron
- Evening (with fats): Astaxanthin, Zinc (away from other minerals)
- Cycling: Tongkat Ali and Fadogia Agrestis 4 weeks on, 1 week off
Timeline for Results: Expect initial improvements in energy and mood within 1-2 weeks. Significant testosterone optimization typically occurs over 4-8 weeks of consistent supplementation combined with proper sleep, nutrition, and exercise.
"Consistency beats perfection. Taking these supplements regularly with a foundation of good sleep and exercise will deliver far better results than perfect timing with inconsistent use."
What to Expect and How to Measure Progress
Natural testosterone optimization is a gradual process, not an overnight transformation. Focus on subjective improvements in energy, mood, and performance rather than obsessing over blood test numbers initially.
- Week 1-2: Improved sleep quality, reduced stress response
- Week 3-4: Increased energy, better mood and motivation
- Week 5-8: Enhanced strength, muscle recovery, and libido
- Week 8+: Optimized body composition and sustained vitality
Consider baseline blood work if you suspect clinically low testosterone (below 300 ng/dL). However, most men will experience significant quality of life improvements even if their levels move from "low normal" to "optimal normal" ranges.
Remember that supplements work best as part of a comprehensive approach including adequate sleep (7-9 hours), regular strength training, stress management, and proper nutrition. These supplements amplify the effects of a healthy lifestyle but don't replace it.